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Found 10 dataset(s) matching "high-throughput toxicity testing".
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Previous work identified a ‘cytotoxic burst’ (CTB) phenomenon wherein large numbers of the ToxCast assays begin to respond at or near test chemical concentrations that elicit cytotoxicity, and a...
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Data for "Smeltz MG, Clifton MS, Henderson WM, McMillan L, Wetmore BA. Targeted Per- and Polyfluoroalkyl substances (PFAS) assessments for high throughput screening: Analytical and testing...
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Supplementary Files 1-15 contain the generated assay data that was used to establish BMAD and determine treatment effects. The tabbed spreadsheet data is formatted so that it can be directly...
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This high-throughput method will be useful in rapid evaluation of chemicals for nuclear receptor activity for multiple species of interest. The modular design of the assay also permits ready...
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EPA researchers have been using advances in computational toxicology to address lack of data on the thousands of chemicals. EPA released chemical data on 1,800 chemicals. The 1,800 chemicals were...
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Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
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Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here, concentration-dependent responses...
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Supplemental data for "Schaupp CM, Maloney EM, Mattingly K, Olker JH, Villeneuve DL. Comparison of in silico, in vitro, and in vivo toxicity benchmarks suggests a role for ToxCast data in...
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The zip file enclosed contains README_Gamble_DevTox GLR_Sup Data_v1.docx, Gamble_DevTox GLR_Sup Fig_Submission_v1.docx, Gamble_DevTox GLR_Tables_Submission_v1.xlsx, Gamble_DevTox GLR_Sup...
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Groundwater samples were collected in June 2018 from a background (reference) well located 200 m upgradient from the source and five wells along a flowline in the plume at 39, 68, 102, 125, and...