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Found 32 dataset(s) matching "biotransformation".
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The purpose of this study was to compare two in vitro systems, cryopreserved trout hepatocytes and trout liver S9 fractions, used to predict in vivo levels of biotransformation in fish. This...
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High-resolution mass spectrometry is advantageous for monitoring physiological impacts and contaminant biotransformation products in fish exposed to complex wastewater effluent. We evaluated this...
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This dataset, presented as an Excel spreadsheet, contains all data presented as figures and tables in an article by Nichols et al, entitled "In vitro-in vivo extrapolation of hepatic...
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The dataset, which is presented as an Excel spreadsheet, contains all data which is presented as figures in Nichols et al., Measurement of kinetic parameters for biotransformation of polycyclic...
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Supporting information in "Saunders, L.J. and Nichols, J.W. (2023), Models Used to Predict Chemical Bioaccumulation in Fish from in Vitro Biotransformation Rates Require Accurate Estimates of...
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Data for "Kolanczyk RC, Saley MR, Serrano JA, Daley SM, Tapper MA. PFAS Biotransformation Pathways: A Species Comparison Study. Toxics. 2023 Jan 12;11(1):74. doi: 10.3390/toxics11010074. PMID:...
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Organic ultraviolet filters (UVFs; also known as sunscreen agents) used in personal care and consumer products can enter the aquatic environment via wastewater treatment plant effluents or by loss...
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Dataset for "Kolanczyk, R.C.; Solem, L.E.; Schmieder, P.K.; McKim, J.M., III. A Comparative Study of Phase I and II Hepatic Microsomal Biotransformation of Phenol in Three Species of Salmonidae:...
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This file contains data used to generate figures shown in Weitekamp et al. Triclosan-resistant host-associated microbiota perform xenobiotic biotransformations in larval zebrafish. This dataset...
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Dataset for "Kolanczyk, R.C.; Solem, L.E.; Tapper, M.A.; Hoffman, A.D.; Sheedy, B.R.; Schmieder, P.K.; McKim, J.M., III. Sex-Linked Changes in Biotransformation of Phenol in Brook Trout...
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This dataset illustrates relationships between body weight and hepatic phase I and phase II metabolic activity in rainbow trout. This dataset is associated with the following...
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The purpose of is this study was to evaluate the potential for biotransformation in the gastrointestinal tissues (GIT) of fish to impact chemical bioaccumulation. In vitro biotransformation of...
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Feminization of male fish and the role of endocrine-active chemicals in this phenomenon has been an area of intense study for many years. Estrone (E1), a natural steroid, is found in aquatic...
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Understanding biotransformation pathways in aquatic species is an integral part of ecological risk assessment with respect to the potential bioactivation of chemicals to more toxic metabolites....
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With exception of metabolic simulations performed using TIMES (version 2.31.2.82), all work was performed using Python (version 3.10.4) run with IPython (version 8.4.0) in JupyterLab (version...
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This paper describes the results of an international ring trial (round robin study) of in vitro methods used to measure chemical biotransformation in fish. Researchers at six laboratories in the...
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This Excel spreadsheet provides data that appear in Tables 1- 2 and Figures 1-4 of the main document, as well as data that appear in Figures S1-S3 of the Supplementary Information. This dataset...
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This dataset provides measured in vitro intrinsic clearance rates for 54 chemicals tested using isolated hepatocytes from humans, rats, and rainbow trout. The test chemicals were selected to...
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This ScienceHub dataset provides characterization data for a pooled sample of trout liver S9 fractions that was used to study the in vitro intrinsic clearance of selected cationic surfactants. ...
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The microgravity environment aboard the International Space Station (ISS) provides a unique stressor that can help understand underlying cellular and molecular drivers of pathological changes...
