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Toxicity Assessment for EPA's Hydraulic Fracturing Study

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: June 27, 2025 | Last Modified: 2015-06-04
This dataset contains data used to develop multiple manuscripts on the toxicity of chemicals associated with the hydraulic fracturing industry. These manuscripts were developed as part of EPA's larger study on the potential for hydraulic fracturing to impact drinking water resources. For each manuscript, we have provided a separate Excel file containing all of the data used to develop that manuscript. The full list of chemicals and toxicity values used in the development of these manuscripts can also be found online in the draft database for EPA's hydraulic fracturing study (URL provided as part of the dataset). This dataset is associated with the following publications: Yost , E., J. Stanek , R. Dewoskin , and L. Burgoon. Overview of Chronic Oral Toxicity Values for Chemicals Present in Hydraulic Fracturing Fluids, Flowback and Produced Waters. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 50: 4788-4797, (2016). Yost , E., J. Stanek , R. Dewoskin , and L. Burgon. Estimating the Potential Toxicity of Chemicals Associated with Hydraulic Fracturing Operations Using Quantitative Structure Activity Relationship Modeling. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 50(14): 7732-7742, (2016). Yost, E., J. Stanek, and L. Burgoon. A Decision Analysis Framework for Estimating the Potential Hazards for Drinking Water Resources of Chemicals Used in Hydraulic Fracturing Fluids. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 574: 1544-1558, (2016).

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