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Tox21BodyMap: A webtool to map chemical effects on the human body

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: June 27, 2025 | Last Modified: 2020-04-06
This manuscript describes development of a novel tool called Tox21BodyMap. This tool is designed to map biological assay data onto organs of the human body, facilitating predictions between chemical exposure and apical effects. Tox21BodyMap maps chemical effects to biological target tissues uses tissue-specific gene expression and high throughput screening data. High throughput screening sources includes ToxCast and Tox21. Tox21BodyMap is a freely available, online tool. This dataset is associated with the following publication: Borrel, A., S. Auerbach, K. Houck, and N. Kleinstreuer. Tox21BodyMap: A webtool to map chemical effects on the human body. NUCLEIC ACIDS RESEARCH. Oxford University Press, Cary, NC, USA, 48(W1): W472-W476, (2020).

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