Synergistic effects of space radiation and microgravity (miRNA WT and ced-1 mutant)

Published by National Aeronautics and Space Administration | National Aeronautics and Space Administration | Metadata Last Checked: October 27, 2025 | Last Modified: 2025-04-23

Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and microRNA microarray in dauer larvae of Caenorhabditis elegans (C. elegans) that endured spaceflight environment and space radiations environment during 16.5-day Shenzhou-8 space mission were performed. In our study wild type and ced-1 mutant strains of C.elegans endured three conditions during shenzhou-8 spaceflight mission including spaceflight static condition(ss) spaceflight 1-g centrifugal condition(sc) and ground control condition(gc). Limited to the quantity of worm samples we performed technical-repeat test but not sample-repeat test.Accordingly xef xbc x8csix miRNA microarrays were performed.

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Complete Metadata

bureauCode	[ "026:00" ]
identifier	nasa_genelab_GLDS-166_jis2-9sk8
issued	2021-05-21
landingPage	https://data.nasa.gov/dataset/synergistic-effects-of-space-radiation-and-microgravity-mirna-wt-and-ced-1-mutant
programCode	[ "026:005" ]
theme	[ "Earth Science" ]