Secondary screening method for sodium-iodide symporter inhibition utilizing FRTL-5 cells data set

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: June 27, 2025 | Last Modified: 0019-06-09

Data pertaining to a NIS-expressing cell line, FRTL-5 and it's screening capabilities for confirming inhibitors of NIS-mediated iodide uptake. This dataset is associated with the following publication: Buckalew, A., J. Wang, A. Murr, C. Deisenroth, W. Stewart, T. Stoker, and S. Laws. Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay. Archives of Toxicology. Springer, New York, NY, USA, 94(3): 873-885, (2020).

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Complete Metadata

bureauCode	[ "020:00" ]
identifier	https://doi.org/10.23719/1518689
programCode	[ "020:095" ]
references	[ "https://doi.org/10.1007/s00204-020-02664-y" ]
rights	null