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Role of IL-12 in
The present study demonstrates that endogenous production of IL-12 is crucial for survival in Staphylococcus aureus-induced arthritis in mice. Staphylococcal load is enhanced in several organs, because of lack of IL-12. This might be due to decreased production of IFN-γ in IL-12-deficient mice. Although IL-12-deficient mice were exposed to higher staphylococcal load, they demonstrated no increased severity of arthritis as compared with control animals.
Complete Metadata
| bureauCode |
[ "009:25" ] |
|---|---|
| identifier | https://healthdata.gov/api/views/7hsu-7nvc |
| issued | 2025-07-13 |
| landingPage | https://healthdata.gov/d/7hsu-7nvc |
| programCode |
[ "009:048" ] |
| theme |
[ "NIH" ] |