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Patent AT-E400570-T1: [Translated] 2,4,6-TRISUBSUTITUTED PYRIMIDINES AS INHIBITORS OF PHOSPHATIDYLINOSITE (PI)3-KINASE AND THEIR USE IN THE TREATMENT OF CANCER

Published by National Center for Biotechnology Information (NCBI) | U.S. Department of Health & Human Services | Metadata Last Checked: September 06, 2025 | Last Modified: 2025-09-06
The invention concerns pyrimidine derivatives of Formula (I) wherein each of p, R<SUP>1</SUP>, R<SUP>2</SUP>, q, R<SUP>3</SUP>, r, R<SUP>4</SUP>, X<SUP>1 </SUP>and Q<SUP>1 </SUP>have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the production of an anti-proliferative effect in a warm-blooded animal such as man.

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