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Patent AT-E399534-T1: [Translated] DRY POWDER PREPARATIONS FOR PRE-DOSED DRY POWDER INHALERS

Published by National Center for Biotechnology Information (NCBI) | U.S. Department of Health & Human Services | Metadata Last Checked: September 06, 2025 | Last Modified: 2025-09-06
A dry powder medicament preparation is disclosed. Also methods of forming and loading metered doses of the preparation into dose containers intended for insertion into a dry powder inhaler are disclosed. The preparation is adapted for a dose forming process, which may be based on volumetric filling or electro-dynamic deposition of the powder particles, such that a metered dose of the preparation is characterized by having at least one load of held-together particles joined in a macrostructure of predefined dimensions and presenting an intended mechanical strength. The pharmacologically active ingredient presents at least 50% by mass of particles in a typical aerodynamic diameter range from 1 to 5 mum. Furthermore, a dose thus formed is then loaded into a high barrier container.

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