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New insights into the role of lncRNA after spaceflight

Published by Open Science Data Repository | National Aeronautics and Space Administration | Metadata Last Checked: November 01, 2025 | Last Modified: 2025-08-21
We analyzed the transcriptional profile by RNA-sequencing of exosomal content isolated from blood plasma of three astronauts who flew on various ISS missions between 1998-2001. Computational analysis of the transcriptome of these exosomes identified 27 differentially expressed lncRNAs with possible functions and clinical implications.

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