NBDPS Comparison of THM Exposure Metrics

We used exposure data collected for a previous study of DBPs to evaluate how different sources of information impact trihalomethane (THM) exposure estimates, Specifically, we compared gestational exposure estimates to THMs based on water utility monitoring data alone, statistical imputation of daily concentrations to incorporate temporal variability, and personal water consumption and use (bathing and showering). We used Spearman correlation coefficients and ranked kappa statistics to compare exposure classifications. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: Data that CDC collects or holds must be available for data sharing within a year after the data are evaluated for quality and shared with any partners in data collection activity. Because NBDPS data contain PII, NBDPS data are not released publicly. Instead, they are available via a special use agreement. Qualified researchers can be granted access to NBDPS data for analysis through collaboration with one of the Centers for Birth Defects Research and Prevention. The procedure for applying for access to NBDPS data can be found on the NBDPS Public Access Procedures web site: https://www.cdc.gov/ncbddd/birthdefects/nbdps-public-access-procedures.html. Format: This research was conducted with data collected by the CDC-sponsored National Birth Defects Prevention Study (NBDPS). These data include birth data and geocoded residential addresses before and during pregnancy. This dataset is associated with the following publication: Luben, T., R. Shaffer, E. Kenyon, W. Nembhard, K. Weber, J. Nuckols, and J. Wright. Comparison of trihalomethane exposure assessment metrics in epidemiologic analyses of reproductive and developmental outcomes. Journal of Exposure Science and Environmental Epidemiology. Nature Publishing Group, London, UK, 34: 115-125, (2024).

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[
  "https://doi.org/10.1038/s41370-023-00559-5"
]