Impact of Scaling Factor Variability on Risk Relevant Outcomes in Children

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: June 27, 2025 | Last Modified: 2017-10-02

This dataset contains physiologically-based (PBPK) model code and parameter settings supporting the manuscript titled "THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT PHARMACOKINETIC OUTCOMES IN CHILDREN: A CASE STUDY USING BROMODICHLOROMETHANE (BDCM)". This dataset is associated with the following publication: Kenyon, E., J. Lipscomb, R. Pegram, B. George, and R. Hines. THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT PHARMACOKINETIC OUTCOMES IN CHILDREN: A CASE STUDY USING BROMODICHLOROMETHANE (BDCM). TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(2): 347-359, (2019).

Find Related Datasets

Click any tag below to search for similar datasets

Complete Metadata

bureauCode	[ "020:00" ]
describedBy	https://pasteur.epa.gov/uploads/10.23719/1407661/documents/DataDictionary_PediatricScalingVariability.pdf
describedByType	application/pdf
identifier	https://doi.org/10.23719/1407661
programCode	[ "020:096" ]
references	[ "https://doi.org/10.1093/toxsci/kfy236", "https://pasteur.epa.gov/uploads/10.23719/1407661/documents/PedsScalingFactorVariability_ModelSettings%26Inputs.pdf", "https://pasteur.epa.gov/uploads/10.23719/1407661/documents/SupplementalData_PedsScalingVariability.pdf" ]
rights	null