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Endothelial [Ca2+]iis an integrating signal for the vascular tone in rat aortae
Although various endothelium-dependent relaxing factors (endothelial autacoids) are released upon the elevation of endothelial cytosolic free Ca2+concentration (EC [Ca2+]i), the quantitative relationship between EC [Ca2+]iand vascular tone remains to be established. Moreover, whether the basal release of endothelial autacoids is modulated by basal EC [Ca2+]iis still unclear. We assessed these issues by using a novel method that allows simultaneous recording of EC [Ca2+]iand vascular displacement in dissected rat aortic segments.
Complete Metadata
| bureauCode |
[ "009:25" ] |
|---|---|
| identifier | https://healthdata.gov/api/views/4qdm-b9ic |
| issued | 2025-07-14 |
| landingPage | https://healthdata.gov/d/4qdm-b9ic |
| programCode |
[ "009:037" ] |
| theme |
[ "NIH" ] |