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Cell-Based Metabolomics for Untargeted Screening and Prioritization of Vertebrate-Active Stressors in Streams Across the United States

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: June 27, 2025 | Last Modified: 2019-03-22
Extents of impact, as measured by NMR spectroscopy, on the Zebrafish liver cell endogenous metabolite profiles resulting from exposure to the 38 stream waters, along with numbers of anthropogenic organic chemicals detected at each site. Also, a summary of chemicals detected by class is included, along with statistics on their occurances in the group of stressors that most-strongly covary with changes in endogenous metabolite profiles. This dataset is associated with the following publication: Collette, T., D. Ekman, H. Zhen, H. Nguyen, P.M. Bradley, and Q. Teng. Cell-Based Metabolomics for Untargeted Screening and Prioritization of Vertebrate-Active Stressors in Streams Across the United States. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 53(15): 9232-9240, (2019).

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