Adverse Outcome Pathway Database (AOP-DB) version 2

The EPA has developed the Adverse Outcome Pathway Database (AOP-DB) to better characterize adverse outcomes of toxicological interest that are relevant to human health and the environment. Since its inception, the AOP-DB has been developed with the aim of integrating AOP molecular target information with other publicly available datasets to facilitate computational analyses of AOP information. A user application for the AOP-DB has been developed for public accessibility. Potential users of the data (Government, Academic, or Industry scientists and researchers) may investigate specific molecular targets of an AOP, the relation of those gene/protein targets to other AOPs, chemical stressor, pathway, or disease-AOP relationships, for example.

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