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Found 3 dataset(s) matching "voltage-clamp".

Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of K
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06 | Harvested: September 06, 2025 at 08:15 AM
Background Phorbol 12-myristate 13-acetate (PMA) is often used as an activating phorbol ester of protein kinase C (PKC) to investigate the roles of the kinase in cellular functions....
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Does lindane (gamma-hexachlorocyclohexane) increase the rapid delayed rectifier outward K
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06 | Harvested: September 06, 2025 at 07:07 AM
Background The effects of lindane, a gamma-isomer of hexachlorocyclohexane, were studied on transmembrane potentials and currents of frog atrial heart muscle using intracellular...
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Functional analysis of a frame-shift mutant of the dihydropyridine receptor pore subunit (α
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06 | Harvested: September 06, 2025 at 05:20 AM
Background The L-type Ca2+ channel formed by the dihydropyridine receptor (DHPR) of skeletal muscle senses the membrane voltage and opens the ryanodine receptor (RyR1). This...
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