Search Data.gov

Found 2 dataset(s) matching "t-cell-tolerance".

T cells that are naturally tolerant to cartilage-derived type II collagen are involved in the development of collagen-induced arthritis
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06 | Harvested: September 06, 2025 at 08:01 AM
The immunodominant T-cell epitope that is involved in collagen-induced arthritis (CIA) is the glycosylated type II collagen (CII) peptide 256-270. In CII transgenic mice, which express the...
- html
The role of X-chromosome inactivation in female predisposition to autoimmunity
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06 | Harvested: September 06, 2025 at 09:33 AM
We propose that the phenomenon of X-chromosome inactivation in females may constitute a risk factor for loss of T-cell tolerance; specifically that skewed X-chromosome inactivation in the thymus...
- html