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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06 | Harvested: September 06, 2025 at 07:53 AM

The anti-PM/Scl autoantibodies are known to characterize a subset of autoimmune patients with myositis, scleroderma (Scl), and the PM/Scl overlap syndrome. The major autoantigens that are...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06 | Harvested: September 06, 2025 at 06:59 AM

The antigenic specificity of an unusual antinuclear antibody pattern in three patient sera was identified after separating HeLa-cell nuclear extracts by two-dimensional (2D) gel electrophoresis...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06 | Harvested: September 06, 2025 at 09:34 AM

The autoantigenic polymyositis/scleroderma (PM/Scl) complex was recently shown to be the human homologue of the yeast exosome, which is an RNA-processing complex. Our aim was to assess whether, in...

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