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Found 408 dataset(s) matching "metabolism".
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The objective of this study was to develop an approach to retrofit existing HTS assays with hepatic metabolism. The Alginate Immobilization of Metabolic Enzymes (AIME) platform encapsulates...
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NHANES data from the 2011-2014 survey years. Specific to adolescents. Ancillary data related to metabolic syndrome and other covariates. This dataset is associated with the following...
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This dataset provides daily metabolism estimates and potential predictor variables to support further exploration. The format is a table with 1 row per site-date combination (1 tab-delimited file,...
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Understanding biotransformation pathways in aquatic species is an integral part of ecological risk assessment with respect to the potential bioactivation of chemicals to more toxic metabolites....
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Background Genome sequencing and bioinformatics are producing detailed lists of the molecular components contained in many prokaryotic organisms. From this 'parts catalogue' of a...
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Ecosystem metabolism is a measure of energy flow in terrestrial and aquatic environments that quantifies a balance between the rate of biomass production by photosynthesizing plants and the rate...
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Effects and interactions between different spaceflight stressors are expected to be experienced by crew on missions when exposed to microgravity and galactic cosmic rays (GCRs). One of the...
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The US EPA’s ToxCast program is designed to assess chemical perturbations of molecular and cellular endpoints using a variety of high-throughput screening (HTS) assays. However, existing HTS...
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This dataset provides details from stream metabolism models for 11 stream sites in Connecticut that were monitored during 2015-2018 by the U.S. Geological Survey. Metabolism was estimated at each...
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Background Several lines of evidence strongly suggest that agouti-related peptide (AGRP) plays a key role in the regulation of metabolic function but ablation of the AGRP gene has no...
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This dataset provides details from stream metabolism models for 20 stream sites in the United States that were sampled as part of the National Water Quality Program's Regional Stream Quality...
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Data were collected between 2013 and 2022 in a research area of the Everglades known as the Decompartmentalization Physical Model (DPM), a wetland area in the central Everglades that includes...
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Background In global gene expression profiling experiments, variation in the expression of genes of interest can often be hidden by general noise. To determine how biologically...
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In this study, using male Wistar and Wistar-derived Goto-Kakizaki (GK) rats, which exhibit a non-obese type-2 diabetes phenotype, we investigated whether two key metabolic stressors, type-2...
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<p dir="ltr">This dataset contains the raw data (unsubstracted) and the machine normalized (subtracted) output files from calorimetry experiments measuring metabolic heat flow of the sugarbeet...
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Background PKQuest, a new physiologically based pharmacokinetic (PBPK) program, is applied to human ethanol data. The classical definition of first pass metabolism (FPM) based on the...
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With exception of metabolic simulations performed using TIMES (version 2.31.2.82), all work was performed using Python (version 3.10.4) run with IPython (version 8.4.0) in JupyterLab (version...
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The space environment astronauts experience during space missions consists of multiple environmental challenges, including microgravity. In this study, we assessed the behavioral and cognitive...
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Air pollution has been associated with metabolic diseases and hepatic steatosis-like changes. We have shown that ozone alters liver gene expression for metabolic processes through neuroendocrine...
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This dataset provides input data formatted for use in estimating metabolism. The format is tables of prepared time series inputs (1 tab-delimited file per site, in 1 zip file per site). This...
