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Found 38 dataset(s) matching "liver toxicity".
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The single database is in an excel file and includes data on elements occurring in keratin, liver, and kidneys of 46 Agassiz’s desert tortoises salvaged from the Mojave and Colorado deserts of...
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The toxicity of liver and kidney upon acute and subacute exposure to bromochloromethane in both male and female rats. This dataset is associated with the following publication: Simmons, J., T....
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General toxicology, clinical chemistry, complete blood counts, histopathology, gene expression. This dataset is associated with the following publication: Chernoff, N., D. Hill, I. Chorus, D....
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Dataset includes summary statistics (mean, standard error, sample size) for all endpoints measured and reported in the experiments described in the published manuscript. This dataset is...
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Production of per- and polyfluoroalkyl substances (PFAS) has shifted from long-chain perfluoroalkyl acids to short-chain compounds and those with ether bonds in the carbon chain. Next-generation...
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These data represent underlying data generated for the study titled 'Extracellular Vesicles altered by Per- and Polyfluoroalkyl Substance Mixtures: In Vitro Dose-Dependent Release, Chemical...
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Dataset includes summary statistics (mean, standard error, sample size) for all endpoints measured and reported from the the experiments described in the published manuscript. This dataset is...
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Acetaminophen overdose is common and can result from deliberate/nonstaggered or accidental/staggered ingestion. Patients presenting within 24 h of an acetaminophen overdose can safely be managed...
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Current studies on nontarget analysis and toxicities of PFASs are disconnected, due to the challenges posed by the large numbers (>1,000) and diverse structures of PFASs. The SECC method provides...
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This repository contains the necessary data, python source code and jupyter notebooks to reproduce the results from our manuscript, "Estimating Hepatotoxic Doses Using High-content Imaging in...
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Data for "Addicks GC, Rowan-Carroll A, Reardon A, Leingartner K, Williams A, Meier MJ, Moffat I, Carrier R, Lorusso L, Wetmore BA, Yauk C, Atlas E. Per- and Polyfluoroalkyl Substances (PFAS) in...
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Supplementary Files 1-15 contain the generated assay data that was used to establish BMAD and determine treatment effects. The tabbed spreadsheet data is formatted so that it can be directly...
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This dataset documents histopathological changes in liver, kidney, skeletal muscle and intestine of captive American kestrels (Falco sparverius) exposed to brodifacoum formulations with differing...
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Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
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This dataset was prepared from the US Environmental Protection Agency's (EPA) Toxicity Reference Database (ToxRefDB) that contains information for 1,142 chemicals and 5,960 studies. Curations...
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Physiological endpoints observed in adult largemouth bass in response to an EE2 (17 alpha-ethinylestradiol) or mixture of estrone and atrazine exposure under laboratory pond conditions. Also...
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Background Electroporation of skeletal muscle after injection of naked DNA was shown by others to increase transgene expression. Information regarding tissue damage caused by...
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The exposure of white-footed mice (Peromyscus leucopus) to lead and cadmium and the potential associated toxic effects were examined at three sites contaminated with lead in the Southeast Missouri...
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Estuaries provide critical habitat for a vast array of fish and wildlife but are also a nexus for core economic activities that mobilize and concentrate contaminants that can threaten aquatic...
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Our research used a combination of laboratory-based acute aqueous metals exposures and RNA-sequencing technologies to identify a gene-based means to extrapolate metals toxicity across a range of...