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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06 | Harvested: September 06, 2025 at 08:08 AM

Genes in the human leukocyte antigen (HLA) region remain the most powerful disease risk genes in rheumatoid arthritis (RA). Several allelic variants of HLA-DRB1 genes have been associated with RA,...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06 | Harvested: September 06, 2025 at 08:17 AM

Giant cell arteritis (GCA) (temporal arteritis) and polymyalgia rheumatica (PMR) are common, frequently related conditions in people generally over 50 years of age. Most studies have shown an...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06 | Harvested: September 06, 2025 at 09:11 AM

The influence of HLA DRB1 alleles on B-cell homeostasis was analyzed in 164 patients with rheumatoid arthritis (RA). The percentages of CD19+ B lymphocytes determined in the peripheral circulation...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06 | Harvested: September 06, 2025 at 08:40 AM

Background Since contradictory results have been reported, we reanalysed the 77C→G transition in exon 4 of the protein-tyrosine phosphatase receptor-type C (PTPRC also known as CD45) in...

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