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Found 3 dataset(s) matching "gene-silencing".

Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06 | Harvested: September 06, 2025 at 08:34 AM
Background Post-transcriptional gene silencing (PTGS) by short interfering RNA has opened up new directions in the phenotypic mutation of cellular genes. However, its efficacy on...
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Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06 | Harvested: September 06, 2025 at 09:33 AM
RNAi can be achieved by feeding worms Escherichia coli expressing dousble-stranded RNA corresponding to a specific gene. An optimized feeding method is presented that results in phenotypes at...
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Retrovirus-delivered siRNA
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-29 | Harvested: September 30, 2025 at 05:21 AM
The ability of transfected synthetic small interfering (si) RNAs to suppress the expression of specific transcripts has proved a useful technique to probe gene function in mammalian cells....
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