Catalog - Data.gov

Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis

Organization: U.S. Department of Health & Human Services
Updated: 2025-09-06 | Harvested: September 06, 2025 at 05:58 AM

Rheumatoid arthritis (RA) patients experience a markedly increased frequency of cardiovascular disease. We evaluated cardiovascular risk profiles in 79 RA patients and in 39 age-matched and...

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The association between secondhand smoke and the risk of developing acute coronary syndromes, among non-smokers, under the presence of several cardiovascular risk factors: The CARDIO2000 case-control study

Organization: U.S. Department of Health & Human Services
Updated: 2025-09-06 | Harvested: September 06, 2025 at 10:27 AM

Background The purpose of this study was to investigate the association between secondhand smoke and the risk of developing a first event of acute coronary syndromes (ACS), i.e. acute...

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Long-term vitamin E supplementation fails to reduce lipid peroxidation in people at cardiovascular risk: analysis of underlying factors

Organization: U.S. Department of Health & Human Services
Updated: 2025-09-06 | Harvested: September 06, 2025 at 08:27 AM

Background Antioxidant supplementation with vitamin E had no effect in the prevention of cardiovascular diseases (CVD) in three recent large, randomized clinical trials. In order to...

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Debate: "How low should LDL cholesterol be lowered?" Viewpoint: "It doesn't need to be very low"

Organization: U.S. Department of Health & Human Services
Updated: 2025-09-06 | Harvested: September 06, 2025 at 07:03 AM

The importance of low-density lipoprotein (LDL) control in the management of patients at high risk of cardiovascular events is unquestionable. The major statin trials have shown that the benefits...

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How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-Up Study (Syst-Eur 2)

Organization: U.S. Department of Health & Human Services
Updated: 2025-09-06 | Harvested: September 06, 2025 at 07:44 AM

Background The randomised, double-blind, placebo-controlled Systolic Hypertension in Europe trial (Syst-Eur 1) proved that blood pressure (BP) lowering therapy starting with nitrendipine...

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Diagnostic strategies for C-reactive protein

Organization: U.S. Department of Health & Human Services
Updated: 2025-09-06 | Harvested: September 06, 2025 at 04:37 AM

Background Serum C-reactive protein (CRP) has been identified in prospective epidemiological research as an independent risk marker for cardiovascular disease. In this paper, short-term...

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Design and intermediate results of the Lower Extremity Arterial Disease Event Reduction (LEADER)* trial of bezafibrate in men with lower extremity arterial disease [ISRCTN41194621]

Organization: U.S. Department of Health & Human Services
Updated: 2025-09-06 | Harvested: September 06, 2025 at 04:51 AM

Background Raised levels of both triglycerides and fibrinogen, each of which are reduced by bezafibrate, may contribute to lower extremity arterial disease (LEAD). This condition is...

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