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Found 2067 dataset(s) matching "bioactivity".
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Read-across is a popular data gap filling technique within category and analogue approaches for regulatory purposes. Acceptance of read-across remains an ongoing challenge with several efforts...
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The present study highlights the utility of bioeffects-based monitoring in conjunction with analytical chemical measurements of surface waters on the Colorado River associated with a historically...
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In the present study, we adapted an existing phenotypic profiling assay (“Cell Painting”, (Bray et al., 2016)) to be compatible with in-house microfluidics capabilities for 384-well culture...
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Data release including concentrations of bioactive organic contaminants in water and sediment and biodegradation rates of select model contaminants in sediment from Congaree National Park during...
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Dataset consists of high throughput in vitro bioactivity data and exposure predictions from the U.S. EPA’s Toxicity and Exposure Forecaster (ToxCast and ExpoCast) project. This dataset is...
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In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a nationwide screen of United States stream water samples. In vitro bioassays...
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Dataset for Jesse Rogers et al., 'Integrating Transcriptomic and Targeted New Approach Methodologies into a Tiered Framework for Chemical Bioactivity Screening' published in Environmental Health...
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The files and .R scripts here are provided to aid in understanding and reproduction of the analyses in the submitted paper, "Examining the Utility of In Vitro Bioactivity as a Protective Point of...
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Dataset for Jurgelewicz, A. et al, 'Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays' published in Toxicology, Vol 517,...
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The data set contains data for the following assays performed using 6PPD-quinone and/or 6PPD. 1) Larval fathead minnow transcriptomics; 2) larval fathead minnow EcoToxChips [6PPD-quinone only];...
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The ToxCast program has generated in vitro screening data on over a thousand chemicals to assess potential disruption of important biological processes and assist in hazard identification and...
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Two non-native bigheaded carp species have invaded the Illinois River system and are a potential threat to the Great Lakes ecosystem. Discharges from industry, wastewater treatment plants, and...
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The dataset is an excel spreadsheet containing the raw data used to generate the tables and figures in the manuscript. This dataset is associated with the following publication: Thompson, L., J....
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All of the code used to analyze and report the data as well as build confidence in the approach is available as a supplementary RMarkdown report, and a tool to derive PODBioactivity...
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Bioactivity data for p,p'-DDD and analogues from ToxCast assays conducted in liver cells were sourced from the EPA’s CompTox Chemistry Dashboard. The links also provide access to the ToxCast assay...
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As a case study, chemical occurrence data from a 2012 study in the Great Lakes Basin along with the ToxCast™ effects database were used to calculate exposure-activity ratios (EARs) as a...
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In vitro biological activity data from a extracts of a nationwide survey of US streams. This dataset is associated with the following publication: Blackwell, B., G. Ankley, P. Bradley, K. Houck,...
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*********** Note to Josh Harrill- I don't have a copy of the final manuscript so could you please add the description of this dataset (just delete this comment and enter or cut and paste and then...
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Water and sediment was collected to assess the occurrence of contaminants of emerging concern (CECs) in National Park waters of the northern Colorado Plateau, USA. CEC presence in water and...
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ToxCast bioactivity data and model predictions for the ER and AR pathways for p,p'-DDD and analogues
ToxCast bioactivity data and model predictions for the estrogen receptor (ER) and androgen receptor (AR) pathways were obtained from the inks provided. This dataset is associated with the...
