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Found 17 dataset(s) matching "ToxRefDB".
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ToxRefDB comprises information from over fifty years of in vivo toxicity data. The database includes information for over 1000 chemicals, and is being used as a primary source of data for...
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This dataset was prepared from the US Environmental Protection Agency's (EPA) Toxicity Reference Database (ToxRefDB) that contains information for 1,142 chemicals and 5,960 studies. Curations...
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The Toxicity Reference Database (ToxRefDB) contains approximately 30 years and $2 billion worth of animal studies. ToxRefDB allows scientists and the interested public to search and download...
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We use a supervised machine learning strategy to systematically investigate the relative importance of study type, machine learning algorithm, and type of descriptor on predicting in vivo...
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In an effort to address a major challenge in chemical safety assessment, alternative approaches for characterizing systemic effect levels, a predictive model was developed. Systemic effect levels...
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The data used are from curation of legacy studies and stored in ToxRefDB. This dataset is associated with the following publication: Pham, L.L., S. Watford, P. Pradeep, M. Martin, R. Thomas, R....
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Data from a study to critically examine some of the issues of using data from ToxRefDB, a database largely composed of guideline studies for pesticidal active ingredients, using a case study...
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All data used for these analyses are publicly available, either through CPDat, ToxRefDB, or the CompTox Chemicals Dashboard. Script associated with these analyses are publicly available through...
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Per Imran Shah, this was the Data used in and published as supplemental material for this manuscript. Table S1. Aggregated point of departure (POD) data obtained from ToxRefDB v2.0. Table S2....
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ToxCast is used as a cost-effective approach for efficiently prioritizing the toxicity testing of thousands of chemicals. It uses data from state-of-the-art high throughput screening (HTS)...
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Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from over 1,000 public sources on...
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Background: Trends in male reproductive health have been reported for increased rates of testicular germ cell tumors, low semen quality, cryptorchidism, and hypospadias, which have been associated...
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A data set of 500 chemicals evaluated for their ability to induce cleft palate in animal prenatal developmental studies was compiled from Toxicity Reference Database and the biomedical literature,...
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Two datasets are included: 1) A collection of datasets (“APROBA HAWC Export 8May2024.xlsx” with accompanying glossary) obtained from study reports available on the National Toxicology Program’s...
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Supplementary data for "Tia Tate, Grace Patlewicz, Imran Shah, A comparison of machine learning approaches for predicting hepatotoxicity potential using chemical structure and targeted...
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This work estimates benchmarks for new approach method (NAM) performance in predicting organ-level effects in repeat dose studies of adult animals based on variability in replicate animal studies....
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The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content underpinning the Dashboard has been...
