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Found 19764 dataset(s) matching "biologic".
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The objective of the RR-23 mission was to better understand the effects of spaceflight on the eyes, specifically on the structure and function of the arteries, veins, and lymphatic vessels that...
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GENE-TOX provided genetic toxicology (mutagenicity) test data from expert peer review of open scientific literature for more than 3,000 chemicals from the United States Environmental Protection...
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The objective of the Rodent Research-7 mission (RR-7) was to study the impact of the space environment on the gut microbiota of two strains of mice and how any changes in-turn affect the immune...
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We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) iron (56Fe) particles 1,...
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With technological advancements, human's desire to explore space is growing and more people are staying longer at the international space station (ISS). The impact of microgravity on stem cells...
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Premise of the study: The root apex is an important region involved in environmental sensing, but comprises a very small part of the root. Obtaining root apex transcriptomes is therefore...
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Draft genome sequences of Fungi isolated from Mars 2020 Spacecraft assembly facility are reported. The fungal strains were isolated from samples collected from cleanroom surfaces of Kennedy Space...
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While it has been shown that astronauts suffer immune disorders after spaceflight, the underlying causes are still poorly understood and there are many variables to consider when investigating the...
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The whole-genome sequences (WGS) of three pathogenic bacterial strains collected from the International Space Station (ISS) were generated and identified as being part of Class...
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Constraint-Based Multiple Alignment Tool (COBALT) is a protein multiple sequence alignment tool that finds a collection of pairwise constraints derived from conserved domain database, protein...
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This ground-based program was intended to address the etiology of visual system structural and functional changes observed in astronauts during both inflight and postflight periods. Using the...
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The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration spaceflight, particularly visual...
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In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are as follows: (a) Spaceflight...
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Light has a principal role in the Arabidopsis transcriptomic response to the spaceflight environment
The Characterizing Arabidopsis Root Attractions (CARA) spaceflight experiment provides comparative transcriptome analyses of plants grown in both light and dark conditions within the same...
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The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue regeneration in space. To this end,...
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The purpose of this study was to determine whether the spaceflight environment induces oxidative damage on ocular structure and how gene expression profiles change during spaceflight.
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Adult and neonatal human cardiovacular progenitor cell clonal populations were flown aboard the ISS for 12 days prior to fixation in RNAprotect. Gene expression analysis was performed against...
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The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to mitigate muscle wasting. The...
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The Spacelab Life Sciences (SLS) program was a series of payloads that used the facilities of an entire Spacelab module to conduct a variety of life science investigations. The general objective...
