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Found 1270 dataset(s) matching "pathways".
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Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of 2100 nuclear genes encoding...
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Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
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Background The Hedgehog (Hh) signaling pathway is vital to animal development as it mediates the differentiation of multiple cell types during embryogenesis. In adults, Hh signaling can...
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Background We previously reported that the α-1 chain of type 11 collagen (COL11A1), not normally expressed in the colon, was up-regulated in stromal fibroblasts in most sporadic...
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A major goal of juvenile justice reform is to reduce reoffending and recidivism among juvenile offenders. Advocates of trauma informed practices assert that disproportionately high rates of...
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Background: The radiation bystander response is an important component of the overall response of cells to radiation and critical to understanding health risks of radiation exposure to humans. The...
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The Maumee River and associated tributaries are an example of a system influenced by a mosaic of contaminant inputs from point and nonpoint sources along a gradient of land uses. To assess the...
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This review focuses on the mechanisms of stress response in the synovial tissue of rheumatoid arthritis. The major stress factors, such as heat stress, shear stress, proinflammatory cytokines and...
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The functional genomic response of developing embryonic submandibular glands to NF-kappaB inhibition
Background The proper balance between epithelial cell proliferation, quiescence, and apoptosis during development is mediated by the specific temporal and spatial appearance of...
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The submitted information includes the final report and the supporting datasets in Excel format. Submitted data includes: - an Excel based techno-economic model with input-output (IO) analysis,...
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This archival information package contains NetCDF files of monthly mean precipitation and sea level pressure model output. The precipitation grid is centered over South Africa and the more...
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<p>The small hive beetle (<em>Aethina tumida</em>, ATUMI) is an invasive parasite of bee colonies. ATUMI feeds on both fruits and bee nest products, facilitating its spread and increasing its...
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The Fremont Bridge Bicycle Counter began operation in October 2012 and records the number of bikes that cross the bridge using the pedestrian/bicycle pathways. Inductive loops on the east and west...
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The Spokane Bridge Bicycle Counter records the number of bikes that cross the bridge using the pedestrian/bicycle pathway on the south side. Inductive loops on the pathway count the passing of...
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The dataset include the following figures and tables: 1)Changes in protein expression of the 14 pathway regulators induced by Ni (II). 2)Hierarchical clustering of 12 differentially expressed or...
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Cytokines play a critical role in the normal development and function of the immune system. On the other hand, many rheumatologic diseases are characterized by poorly controlled responses to...
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As a case study, chemical occurrence data from a 2012 study in the Great Lakes Basin along with the ToxCast™ effects database were used to calculate exposure-activity ratios (EARs) as a...
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This study demonstrates the potential of whole-mount in situ hybridization (WISH), in conjunction with quantitative real-time polymerase chain reaction (QPCR) assays, to examine the mechanistic...
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Prioritization of chemicals was performed on two Areas of Concerns in the Great Lakes An integrated risk surveillance and monitoring approach was applied Bio-effect prediction methodologies were...
