Search Data.gov
Found 130 dataset(s) matching "signaling pathways".
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Background Serotonin (5-HT, 5-hydroxytryptamine) activates the Extracellular Signal-Regulated Kinase (ERK)/ Mitogen-Activated Protein Kinase (MAPK) pathways, in vascular smooth muscle...
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metadata sheet, data sheet for each table and figure in the published manuscript. This dataset is associated with the following publication: Gray , E., J. Furr , K. Tatum-Gibbs, C. Lambright ,...
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There is growing evidence that activated synovial fibroblasts, as part of a complex cellular network, play an important role in the pathogenesis of rheumatoid arthritis. In recent years,...
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Background Alternative exons encode different isoforms of the human insulin-like growth factor-I (IGF-I) precursor without altering mature IGF-I. We hypothesized that the various IGF-I...
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It is not known to what extent glucocorticoid hormones cause their anti-inflammatory actions and their undesirable side effects by the same or different molecular mechanisms. Glucocorticoids...
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Background Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known of the Wnt...
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canonical pathways for each concentration of nano Cu and CuCl2 after upload the DEG lists of each concentration to Ingenuity Pathway Analysis
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Dataset for Baker, et al., Identifying candidate reference chemicals for in vitro testing of the retinoid pathway for predictive developmental toxicity, published in journal Altex,...
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Dataset for 'Effects of multi-walled carbon nano tubes on human lung epithelial BEAS-2B cells' journal article by Sheau-Fung Thai, et al., to be published in Materials Express. For the data...
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Data collected during the comparison of ozone responsiveness in primary bronchial epithelial cells from a range of distinct donors. This dataset is associated with the following...
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data was from HepG2 cells treated with nano-silver particles using silver nitrate as negative controls. Differentially expressed messenger RNA and microRNA were obtained by RNA sequencing and...
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Differential expressed gene lists and altered canonical pathways in HepG2 cells after CeO2 particle treatment. This dataset is associated with the following publication: Thai, S., C. Jones, B....
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Background Expression profiling holds great promise for rapid host genome functional analysis. It is plausible that host expression profiling in an infection could serve as a universal...
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Background The mammalian homologue of Seven in Absentia (Siah) can act in the ubiquitin/proteasome pathway. Recent work has shown that Siah can bind group I metabotropic glutamate...
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Background Numerous investigations demonstrate a novel role of thyroid hormone as a modulator of signal transduction. Protein kinase C (PKC) is critical to the mechanism by which thyroid...
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Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling. Thus identification and...
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Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling. Thus identification and...
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Background Microarray experiments offer a potent solution to the problem of making and comparing large numbers of gene expression measurements either in different cell types or in the...
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The health risk from spaceflight-induced neuronal damage and potential adverse neurovascular effects is a chief concern. More recently, it has been proposed that neuroinflammatory response plays...
