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Found 136 dataset(s) matching "estrogens".
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Spontaneous premature ovarian failure presents most commonly with secondary amenorrhea. Young women with the disorder are infertile and experience the symptoms and sequelae of estrogen deficiency....
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Tamoxifen, a potent anticancer agent known to interrupt the enhanced estrogen activity of malignant mammary gland cells, was recently approved by the Food and Drug Administration (FDA) for the...
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For decades, induction of vitellogenin (VTG), a yolk precursor protein, in male fish has been utilized as an indicator of environmental exposure to estrogenic compounds. VTG has been measured by a...
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This is a collection of data on the contamination of water, fish, and sediments in Biscayne National Park and in canals that discharge into the national park. The water data are estimations of...
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We have adapted two commonly used human breast luciferase transactivation cell bioassays, the recently re-named estrogen agonist/antagonist screening VM7Luc4E2 cell bioassay (previously designated...
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Five chemicals [2-ethylhexyl 4-hydroxybenzoate (2-EHHB), 4-nonylphenol-branched (4-NP), 4-tert-octylphenol (4-OP), benzyl butyl phthalate (BBP) and dibutyl phthalate (DBP) were subjected to a...
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Detected in vitro estrogen, androgen, and glucocorticoid receptor activity,in samples in the 2018 tapwater study in Cape Cod, Massachusetts. This dataset is associated with the following...
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Chemical and biological results, quality assurance and quality control, and method information from groundwater, surface water, and litter samples, collected from nine locations in Iowa and one in...
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This dataset contains raw and reduced GC and LC data in an excel file. This dataset is associated with the following publication: Serrano, J., R. Kolanczyk, M. Tapper, T. Lahren, N. Dongari, D....
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In 2016, smallmouth bass were collected from three sites in the Lake Erie drainage in Erie County, Pennsylvania and an out-of-basin site in the Allegheny River drainage in order to assess...
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The data presented include concentrations of 122 organic, 23 inorganic constituents, and estrogenicity in water collected from 13 off-stream non-point source sites (natural and created wetlands)...
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The data include concentrations of current use pesticides in tissues of larval wood frog (Lithobates sylvaticus) and spotted salamander (Ambystoma maculatum) and the presence of ranavirus in wood...
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In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a pilot study of US tapwaters. In vitro bioassays include T47D-Kbluc, MDA-kb2, and...
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This dataset contains the concentration and quality assurance results for inorganic and organic analytes collected for the U.S. Geological Survey (USGS), Ecosystems Mission Area, Environmental...
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Adult largemouth bass have been shown to be sensitive to induction of intersex in response to chronic estrogen exposures over a complete reproductive cycle. Late summer to fall is the period of...
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These data are from two studies conducted to evaluate the performance of the draft Larval Amphibian Growth and Development Assay for incorporation into the U.S. EPA's Endocrine Disruptor Screening...
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Male adult FHM liver treated with EE2 - gene expresssion - Agilent-036574 FHM_8x60K_V2 array design. This dataset is associated with the following publication: Feswick, A., M. Isaacs, A. Biales,...
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This data includes metabolite predictions for in vitro inactive chemicals, predictions of those metabolite's estrogen receptor binding activity, in vitro and in silico information regarding parent...
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The objectives of this work were to: 1) develop an integrated analysis of chemical-mediated effects on steroidogenesis in the HT-H295R assay; and, 2) evaluate whether the HT-H295R assay predicts...
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A dataset for the manuscript which demonstrates that it is possible to achieve levels of performance equivalent to the full 16 assay ER agonist model against both in vitro and in vivo reference...
