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Found 312 dataset(s) matching "Transcriptomics.".
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This study examined effects of the brominated flame retardant hexabromocyclododecane (HBCD) on the avian endocrine system. Japanese quail (Coturnix japonica) were exposed to multiple doses of HBCD...
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Our research used a combination of laboratory-based acute aqueous metals exposures and RNA-sequencing technologies to identify a gene-based means to extrapolate metals toxicity across a range of...
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Supplemental datafiles for journal article 'High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells'.
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Martian regolith (unconsolidated surface material) is a potential medium for plant growth in bioregenerative life support systems during manned missions on Mars. However, hydrated magnesium...
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Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological samples here. Mice were exposed...
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Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological samples here. Mice were exposed...
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Translating fundamental biological discoveries from NASA Space Biology program into health risk from space flights has been an ongoing challenge. We propose to use NASA GeneLab database to gain...
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<p dir="ltr">Kafirin data generated by co-author Scott Bean from the manuscript as part of manuscript characterizing the transcriptome and metabolome of sorghum during seed development. </p><p><br></p>
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In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due to age, twenty 12 week-old and...
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Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading to loss of muscle mass and...
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Rapid heating events, such as heatwaves, are becoming more frequent and intense as a result of climate change. Importantly, such extreme weather events can be more important drivers of extirpation...
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Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology, yet the apparent components of hypobaria are stresses typical of terrestrial ecosystems....
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Dataset used to determine the predictive accuracy of the HDACi biomarker. This dataset is associated with the following publication: Cho, E., A. Rowan-Carroll, A. Williams, C. Corton, H. Li, A....
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<p>RNA expression analysis was performed on the corpus luteum tissue at five time points after prostaglandin F2 alpha treatment of midcycle cows using an Affymetrix Bovine Gene v1 Array. The...
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Gene Expression Omnibus and ArrayExpress archived study numbers of microarray data used in the study. This dataset is associated with the following publication: Rooney, J., B. Chorley, S....
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This experiment compared the spaceflight transcriptomes of four commonly used natural variants (ecotypes) of Arabidopsis thaliana using RNAseq. In nature, Arabidopsis is a native of...
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Low RNA yield and quality limit use of formalin-fixed paraffin-embedded (FFPE) tissue samples for genomic analyses. In this study, we evaluated methods to demodify RNA highly fragmented and...
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Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology, yet the apparent components of hypobaria are stresses typical of terrestrial ecosystems....
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The BRIC-21 mission was designed to identify the response of Bacillus subtilis to the human spaceflight environment. For this mission, samples were grown in rich-medium using the Biological...
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The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue regeneration in space. To this end,...