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Found 437 dataset(s) matching "receptor.".
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This dataset is from screening 94 diverse chemicals for estrogen receptor (ER) activation in a competitive rainbow trout ER binding assay and a trout liver slice vitellogenin mRNA expression...
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CEACAM1 is a member of the carcinoembryonic antigen (CEA) family. Isoforms of murine CEACAM1 serve as receptors for mouse hepatitis virus (MHV), a murine coronavirus. Here we report the crystal...
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<p>A GeXP multiplex, RT-PCR assay was developed and optimized that simultaneously measures expression of a suite of immune-relevant genes in rainbow trout (<em>Oncorhynchus mykiss</em>),...
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The invention concerns new tumor necrosis factor receptor associated factors, designated TRAFs. The new factors are capable of specific association with the intracellular domain of the type 2 TNF...
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Ongoing honey bee colony losses are of significant international concern because of the essential role these insects play in pollinating many high nutrient crops, such as fruits, vegetables, and...
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Supporting Information for "Jensen, M.A., Blatz, D.J. and LaLone, C.A. (2023), Defining the Biologically Plausible Taxonomic Domain of Applicability of an Adverse Outcome Pathway: A Case Study...
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Introduction Treatment of patients with severe sepsis with agents antagonising the effects of C5a has been proposed based on beneficial effects in animal experiments and in vitro studies...
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In vitro and in vivo data for the estrogen receptor. The in vivo data is for binding, agonism, and antagonism. The in vivo data is from mouse uterotropic assay data. The following columns are...
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"Morshead ML, Jensen KM, Ankley GT, Vliet S, LaLone CA, Aller AV, Watanabe KH, Villeneuve DL. Putative adverse outcome pathway development based on physiological responses of female fathead...
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The dataset includes data from six experiments in which adult male fathead minnows were exposed to five concentrations of a per- or polyfluorinated alkyl substance (PFAS) and a 17beta-estradiol...
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<p>The Nuclear Receptor Signaling Atlas (NURSA) is designed to foster the development of a comprehensive understanding of the structure, function, and role in disease of nuclear receptors (NRs)...
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This dataset provides Weather Research and Forecasting (WRF) Stochastic Time-Inverted Lagrangian Transport (STILT) Footprint data products for receptors (observations) located at positions along...
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This invention relates to processes for preparing derivatives of 3,6-disubstituted azabicyclo compounds that can function as muscarinic receptor antagonists, and can be used for the treatment of...
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Gene Expression Omnibus (GEO) accession numbers of studies used in the analysis. This dataset is associated with the following publication: Rooney, J., K. Oshida, R. Kumar, W. Baldwin, and C....
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Background Nicotine is a psychoactive drug presenting a diverse array of biological activities, some positive, such as enhancement of cognitive performances, others negative, such as...
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Data sets include 1. Excel file with Hershberger assay protocols and data and summaries of in vivo antiandrogen studies 2. Figures of in vitro AR assay results from contract work and in house...
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Adrenergic and glucocorticoid receptor antagonists reduce ozone-induced lung injury and inflammation
This data set contains one Excel file. In this file are all the data pertaining to the effects of propranolol and mifepristone on ozone induced lung injury and inflammation . The different tabs of...
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Microarray experiments examined in the study. This dataset is associated with the following publication: Rooney, J., N. Ryan, J. Liu, R. Houtman, R. van Beuningen, J. Hsieh, G. Chang, S. Chen,...
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Data on 1855 chemicals were generated during ToxCast Phases I and II and Tox21 screening using 11 AR-related in vitro assays to build a computational network model for AR pathway activity. This...
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Glucocorticoids (GCs) are routinely used as anti-inflammatory drugs in the treatment of asthma. They act through binding to glucocorticoid receptor α (GRα), which represses numerous genes encoding...
