Search Data.gov
Found 105 dataset(s) matching "in vitro model".
-
The dataset has all of the information used to create and evaluate 3 independent QSAR models for the fraction of a chemical unbound by plasma protein (Fub) for environmentally relevant chemicals....
-
Data sets in the context of this project are the model files, model input parameter sets, and data generated at the US EPA/ORD/National Health and Environmental Effects Research Laboratory that...
-
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
-
Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") as in Pearce et al. (2017) <doi:10.18637/jss.v079.i04>. Chemical-specific in vitro data have...
-
Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
-
This dataset consists of data from in vitro developmental neurotoxicity new approach methodologies (DNT-NAMs). Assays include evaluations of proliferation, apoptosis, viability, neurite outgrowth,...
-
A diverse data set of 1667 chemicals with AR experimental activity were provided by the U.S. EPA from the oxicity Forecaster (ToxCast) program which generates data using in vitro high-throughput...
-
There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19) is a steroidogenic enzyme involved in the...
-
Background: Infections after severe brain injury or polytrauma are still a problem, and may be the result of a brain-mediated disturbed systemic immunoreactivity. The mechanism that...
-
Bioaccessibility values for fipronil determined using 37 paired soil and dust samples. Values for the physicochemical properties of the soils and dusts used to model the bioaccessibility data....
-
This work is part of an experimental trial to develop and assess novel recombinant raccoonpox virus (RCN) rabies vaccines in the mouse model, for potential use in bats. Briefly, our research group...
-
Data set includes empirical results from 60 h, 10 d, and 21 d exposures of female fathead minnows to the fungicide imazalil as well as simulations from predictive models anchored to an established...
-
Background Water delivered by dental units during routine dental practice is highly contaminated. The aim of this study is to evaluate the efficacy of a new chemical solution flushed...
-
Background SPARC is a matricellular protein involved in cell-matrix interactions. From expression patterns at the wound site and in vitro studies, SPARC has been implicated in the...
-
Since the publication of the Adverse Outcome Pathway (AOP) for skin sensitization, there have been many efforts to develop systematic approaches to integrate the information generated from...
-
Dataset for 'A high throughput screening assay for human Thyroperoxidase inhibitors' by Hongyan Dong, et al., a collaboration work with primary authorship at Health Canada. Published in Toxicology...
-
This manuscript tests the hypothesis of dose additivity of an environmental mixture of pyrethriod insecticides at the level of network function, in vitro. The results demonstrate that permethrin,...
-
We use a supervised machine learning strategy to systematically investigate the relative importance of study type, machine learning algorithm, and type of descriptor on predicting in vivo...
-
Background: Chemicals in consumer products are a major contributor to human chemical co-exposures. Consumers purchase and use a wide variety of products containing potentially thousands of...
