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Found 105 dataset(s) matching "in vitro model".
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This file contains the analyzed dataset for each figure/table in the manuscript. This dataset is associated with the following publication: Lehmann , D., and W. Williams. Development and...
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The US EPA Toxicity Forecasting (ToxCast) project has involved the generation of large amount of high throughput in vitro data (Over 4000 chemicals tested in between 100 and 700 assays). This data...
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Understanding biotransformation pathways in aquatic species is an integral part of ecological risk assessment with respect to the potential bioactivation of chemicals to more toxic metabolites....
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The purpose of this study was to compare two in vitro systems, cryopreserved trout hepatocytes and trout liver S9 fractions, used to predict in vivo levels of biotransformation in fish. This...
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1) % Viability of human reconstructed skin exposed to cerium, silver and titanium nanoparticles; 2) Zeta potential of the nanoparticles in media. This dataset is associated with the following...
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Background Endothelial MAdCAM-1 (mucosal addressin cell adhesion molecule-1) expression is associated with the oxidant-dependent induction and progress of inflammatory bowel disease...
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Background Recently a hyperthermic rat hippocampal slice model system has been used to investigate febrile seizure pathophysiology. Our previous data indicates that heating immature rat...
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The U.S. Tox21 Federal collaboration, which currently quantifies the biological effects of nearly 10,000 chemicals via quantitative high-throughput screening(qHTS) in in vitro model systems, is...
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Background and methods We report two clinical studies, one already published, performed in patients with early and advanced chronic venous insufficiency (CVI). In both, compression...
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post ingestion bioaccessibility data for pesticides. This dataset is associated with the following publication: Parker, B., E. Valentini, S. Graham, and J. Starr. In vitro modeling of the...
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post ingestion bioaccessibility data for pesticides. This dataset is associated with the following publication: Starr, J., E. Valentini, B. Parker, S. Graham, and F. Waldron. In vitro modeling...
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CD4+ memory T cells (Tm) from rheumatoid arthritis peripheral blood (RAPB) or peripheral blood from normal donors produced IL-2, whereas fewer cells secreted IFN-γ or IL-4 after a brief...
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Background It has been proposed that GL15, a human cell line derived from glioblastoma multiforme, is a possible astroglial-like cell model, based on the presence of cytoplasmic glial...
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A dataset for the manuscript which demonstrates that it is possible to achieve levels of performance equivalent to the full 16 assay ER agonist model against both in vitro and in vivo reference...
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This paper described development of an in vitro/in vivo model that accounts for first pass clearance effects. The model details are contained in the supporting information for the paper. This...
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Background Leishmaniasis is a major parasitic disease in the tropical regions. However, Leishmania infantum has recently emerged as a very important cause of opportunistic infections for...
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Bioaccessibility dat for PCBs and food types. This dataset is associated with the following publication: Starr, J., W. Li, S. Graham, H. Shen, and F. Waldron. Is food type important for in vitro...
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In the present study, we adapted an existing phenotypic profiling assay (“Cell Painting”, (Bray et al., 2016)) to be compatible with in-house microfluidics capabilities for 384-well culture...
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Dataset for manuscript titled, "Ozone responsive gene expression as a model for describing repeat exposure response trajectories and inter-individual toxicodynamic variability in vitro" published...
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A single excel file describes data from the manuscript entitled In vitro effects-based method and water quality screening model for use in pre- and post-distribution treated waters. The file is...