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Found 1270 dataset(s) matching "pathways".
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Production of per- and polyfluoroalkyl substances (PFAS) has shifted from long-chain perfluoroalkyl acids to short-chain compounds and those with ether bonds in the carbon chain. Next-generation...
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This research was designed to evaluate whether a biologically-based computational model aligned with an adverse outcome pathway (AOP) could effectively predict animal (in vivo) responses to...
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In this study, a hypothesized adverse outcome pathway (AOP) linking inhibition of thyroid peroxidase (TPO) activity to impaired swim bladder inflation was investigated in experiments in which...
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These data were compiled as a supplement to a previously published journal article (Bradford et al., 2019), that employed a ecosystem water balance model to characterize current and future...
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These data were compiled based on field observations and available literature. Field observations of plant cover were made in September and October of 2013 and 2014, while trait measurements were...
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The aim of this study was to investigate temporal changes in the hypothalamic-pituitary-gonadal axis of fathead minnow treated with the model androgen receptor (AR) antagonist, flutamide....
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High-resolution maps of big sagebrush plant community biomass using multivariate matching algorithms
These GeoTIFF data were compiled to investigate how a new multivariate matching algorithm transfers simulated plant functional biomass of big sagebrush plant communities from 200 sites to a...
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Background Development of proximal and distal colorectal cancers involve partly different mechanisms associated with the microsatellite instability (MSI) and the chromosomal instability...
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Publicly available genetic sequence data were searched for human sequences that potentially represent protein kinases, important players in virtually every signaling pathway. After removal of...
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High-resolution maps of big sagebrush plant community biomass using multivariate matching algorithms
These GeoTIFF data were compiled to investigate how a new multivariate matching algorithm transfers simulated plant functional biomass of big sagebrush plant communities from 200 sites to a...
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Data set includes empirical results from 60 h, 10 d, and 21 d exposures of female fathead minnows to the fungicide imazalil as well as simulations from predictive models anchored to an established...
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These data were compiled using a new multivariate matching algorithm that transfers simulated soil moisture conditions (Bradford et al. 2020) from an original 10-km resolution to a 30-arcsec...
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These data were compiled for the study: Divergent climate change effects on widespread dryland plant communities driven by climatic and ecohydrological gradients. The objectives of our study were...
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Red lionfish (Pterois volitans) have become a successful invasive predator across the Northwestern Atlantic, Caribbean, and Gulf of Mexico (GoM). Previous investigations have identified the...
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This dataset contains results for samples collected at stormwater basins across the United States to assess the potential contaminant pathways of these basins to surface water and groundwater....
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Data on 1855 chemicals were generated during ToxCast Phases I and II and Tox21 screening using 11 AR-related in vitro assays to build a computational network model for AR pathway activity. This...
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Concentrations of 127 organic chemicals measured in water samples collected from five locations in proximity to two municipal wastewater treatment plants in the St. Croix River basin, MN and WI,...
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This dataset contains ontology terms associated with key events from the AOP-Wiki. This information was used to seed the AOP-Wiki with a carefully selected set of ontology terms prior to opening...
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We examined whether contaminants present in surface waters could be prioritized for further assessment by linking the presence of specific chemicals to gene expression changes in exposed fish....
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The present study investigated whether inhibition of deiodinase, the enzyme which converts thyroxine (T4) to the more biologically-active form, 3,5,3'-triiodothyronine (T3), would impact inflation...
