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Found 1270 dataset(s) matching "pathways".
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Background Two-component systems consisting of histidine kinases and their corresponding receivers are widespread in bacterial signal transduction. In the past few years, genes coding...
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Background The mammalian homologue of Seven in Absentia (Siah) can act in the ubiquitin/proteasome pathway. Recent work has shown that Siah can bind group I metabotropic glutamate...
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The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this signalling pathway might contribute to...
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Background Reversible protein phosphorylation is relatively unexplored in the intracellular protozoa of the Apicomplexa family that includes the genus Plasmodium, to which belong the...
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This dataset provides the number and disposition of child welfare assessments conducted by the Department of Human Services beginning January 1, 2004. On January 1, 2014, the department began...
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Liquid chromatography tandem mass spectrometry allows for the measurement of steroid hormone suites in the blubber of marine mammals. By combining this technology with remote biopsy collection,...
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The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how spaceflight affects...
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Small-molecule antagonists of Hedgehog-pathway signaling, such as cyclopamine, have been known for some time. Now, small-molecule agonists of the Hedgehog pathway have also been identified. The...
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The Africa Climate Mobility Initiative (ACMI) Internal Migration Projections project internal migration flows at 5-year intervals from 2020 to 2050 for a combination of 2 sets of Shared...
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Background Treatment of mouse F9 embryonal carcinoma cells with all-trans retinoic acid (T-RA) induces differentiation into primitive endodermal type cells. Differentiation requires the...
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In response to various legislative mandates the United States Environmental Protection Agency (USEPA) formed its Endocrine Disruptor Screening Program (EDSP), which in turn, implemented a tiered...
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Background Post-transcriptional gene silencing (PTGS) by short interfering RNA has opened up new directions in the phenotypic mutation of cellular genes. However, its efficacy on...
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High-resolution mass spectrometry is advantageous for monitoring physiological impacts and contaminant biotransformation products in fish exposed to complex wastewater effluent. We evaluated this...
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Microphysiological systems provide the opportunity to model accelerated changes at the human tissue level in the extreme space environment. Spaceflight-induced muscle atrophy experienced by...
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Efforts to understand the impact of spaceflight on the human body stem from growing interest in long-term space travel. Multiple organ systems are affected by microgravity and radiation, including...
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Non-EPA data associated with Air Quality, Health, and Equity Benefits of Carbon Neutrality andClean Air Pathways in China. This dataset is not publicly accessible because: Data owned by Tsinghua...
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Background The P-glycoprotein (P-gp), an ATP binding cassette transmembrane transporter, is expressed by astrocytes in the adult brain, and is positively modulated during astrogliosis....
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Parents, siblings, partners, and friends are often the first people to suspect a loved one is on the trajectory towards targeted violence or terrorism. These intimate bystanders are well...
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NITROP - 85 was the major field of experiment of an N.S.F. funded program entitled "Microbial Nitrogen Transformations in the Oxygen Minimum Zone off Peru". This project focused on obtaining a...
