Search Data.gov
Found 250 dataset(s) matching "phenotype".
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Osteoporosis (OP) and osteoarthritis (OA), the two most common age-related chronic disorders of articular joints and skeleton, represent a major public health problem in most developed countries....
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Background Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal storage disorder characterized by severe neurologic and ophthalmologic abnormalities. Recently the MLIV gene,...
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In this study, a hypothesized adverse outcome pathway (AOP) linking inhibition of thyroid peroxidase (TPO) activity to impaired swim bladder inflation was investigated in experiments in which...
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Surfactant protein-D (SP-D) participates in the innate response to inhaled microorganisms and organic antigens, and contributes to immune and inflammatory regulation within the lung. SP-D is...
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Background Genome sequencing and bioinformatics are producing detailed lists of the molecular components contained in many prokaryotic organisms. From this 'parts catalogue' of a...
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- Changes in tissue transcriptomes and productivity of Arabidopsis thaliana were investigated during exposure of plants to two widely used engineered metal oxide nanoparticles, titanium dioxide...
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Background T cells from HIV+ and aged individuals show parallels in terms of suppressed proliferative activity and interleukin-2 (I1-2) production and an increased number of CD8+ CD28- T...
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Bacillus pumilus SAFR-032, an endospore-forming bacterial strain, was investigated to determine its methylation pattern (methylome) change, compared to ground control, after direct exposure to...
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Rapid heating events, such as heatwaves, are becoming more frequent and intense as a result of climate change. Importantly, such extreme weather events can be more important drivers of extirpation...
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<p dir="ltr">This Vitis mapping population consisted of F1 hybrids derived from a cross between female parent ‘Chambourcin’ with a pollen donor ‘Cabernet Sauvignon’. These hybrids were planted at...
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<p>CottonGen (<a href="https://www.cottongen.org">https://www.cottongen.org</a>) is a curated and integrated web-based relational database providing access to publicly available genomic, genetic...
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Background Race is commonly described in epidemiological surveys based on phenotypic characteristics. Training of interviewers to identify race is time-consuming and self identification...
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Background Liver fibrosis is the common sequel of chronic liver diseases. Recent studies have identified hepatic stellate cells as the primary cell type mediating hepatic fibrogenesis....
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Background The hepatic stellate cell is the primary cell type responsible for the excessive formation and deposition of connective tissue elements during the development of hepatic...
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Systemic sclerosis (SSc) is a multisystem connective tissue disease characterised phenotypically by fibrosis and ischaemic atrophy. Its aetiology is most likely multifactorial. A genetic...
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GRAF (Genetic Relationship and Fingerprinting) is a C++ program that quickly finds the closely related subjects, infers subject ancestry, determines subject sexes using genotypes and compares the...
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This population historically migrated as subyearling smolts, but in recent years, the yearling life history has become more common. Environmental conditions associated with dams and reservoirs...
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We are applying a variety of genetic tools to assess the response of our ocean resources to ocean acidification, including gene expression techniques, identification of candidate genes, and...
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We are using genetic pedigree information to estimate the reproductive success of hatchery and wild fall-run Chinook salmon spawning in the Cedar River, Washington. Genotypes and associated...
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The cystic fibrosis transmembrane conductance regulator (CFTR) has been known for the past 11 years to be a membrane glycoprotein with chloride channel activity. Only recently has the...
