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Found 112 dataset(s) matching "In vitro assay".
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Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here, concentration-dependent responses...
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Data for Hopperstad K and Deisenroth C (2023) Development of a bioprinter-based method for incorporating metabolic competence into high-throughput in vitro assays. Front. Toxicol. 5:1196245. doi:...
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Supplementary data for "Stephanie A. Eytcheson, Jennifer H. Olker, Katie Paul Friedman, Michael W. Hornung, Sigmund J. Degitz, Assessing utility of thyroid in vitro screening assays through...
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The US EPA Toxicity Forecasting (ToxCast) project has involved the generation of large amount of high throughput in vitro data (Over 4000 chemicals tested in between 100 and 700 assays). This data...
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A dataset for the manuscript which demonstrates that it is possible to achieve levels of performance equivalent to the full 16 assay ER agonist model against both in vitro and in vivo reference...
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1) % Viability of human reconstructed skin exposed to cerium, silver and titanium nanoparticles; 2) Zeta potential of the nanoparticles in media. This dataset is associated with the following...
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This data set is a dose response analysis of two thyroid hormone synthesis disruptors in adult male rats. Data included serum and thyroid gland concentrations of the two chemicals tested,...
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the data set contains the figures and tables from the publication in addition to the means, standard errors of the mean and the sample sizes used in each group for every experiment. the data set...
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Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
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A representative group of multicyclic aromatic hydrocarbons (MAHC) which can be further classified as bridged-ring (bridged-MAHC) or fused-ring (fused-MAHC) were examined for their ability to...
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This study evaluated two anti-angiogenic agents, 5HPP-33 and TNP-470, across the ToxCastDB HTS assay platform and anchored the results to complex in vitro functional assays: the rat aortic explant...
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In crude-oil-contaminant plumes the dissolved organic carbon (DOC) is mainly hydrocarbon degradation intermediates only partly quantified by the diesel range total petroleum hydrocarbon (TPHd)...
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Background The mos proto-oncogene encodes a cytoplasmic serine/threonine-specific protein kinase with crucial function during meiotic cell division in vertebrates. Based on oncogenic...
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Data sets include 1. Excel file with Hershberger assay protocols and data and summaries of in vivo antiandrogen studies 2. Figures of in vitro AR assay results from contract work and in house...
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Phenones and hydroxy benzophenones are widely used as UV radiation filters, and in the manufacturing of insecticides and pharmaceuticals. Understanding the ability of these chemicals to mimic the...
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This file contains the data on apoptosis, neurite outgrowth, synaptogenesis and proliferation. This dataset is associated with the following publication: Harrill, J., T. Freudenrich, K. Wallace,...
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This dataset contains the raw data, Area under the curve measurements and EC50 values for effects of 146 compounds (136 unique plus 10 biological replicates) on parameters of network development...
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These data are the individual parameter and well-level data that were support the conclusions in Brown et al. Note: the parameters CVtime and CVnetwork were not used. This dataset is associated...
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Dataset for Jurgelewicz, A. et al, 'Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays' published in Toxicology, Vol 517,...
